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Xerosis
Skin structure Skin is composed of three primary layers: the epidermis, which has contact with the outside; the dermis, which contains sebaceous glands ; and the hypodermis-subcutaneous tissue, which is the bottom layer of the skin.
The "epidermis" plays a role as the barrier against external stimulation such as UV, chemical substance andbacteria. The "dermis" is a thick layer containing water and secures the skin's firmness and resilience. It consists of collagen, elastin, hyaluronic acid and chondroitin sulphate etc. It provides essential nourishment and helps to make a coat of sebum which protects the skin by secreting sweat and sebum. And it also contains the lymph vessels, blood vessels, nervus, sebaceous glands and root hair etc. The "hypodermis-subcutaneous tissue" consists almost entirely of subcutaneous fat. It plays an important role as energy storage, a function of maintaining body temperature and a cushion from outside pressures. Sebum and coat of sebum
Sebum is a lipid substance synthesized by sebaceous cells and its main component is the neutral lipid (triglyceride). When sebum is synthesized in large quantities and beyond the amount of accumulation in a cell, sebaceous cells burst and sebum is extruded into the ducts of the sebaceous gland. The sebum is secreted to the skin surface through the pores, making a coat of sebum covering the skin surface. ↓ The decrease of sebum secretion due to stress or aging leads to the failure of the formation of the sebum coat and can easily get external stimulation. When skin is damaged, the evaporation of skin moisture is stimulated, skin metabolism is distorted, moisturizing and excretory functions also become lower. This then leads to skin problems such as dry skin, tiny wrinkles and skin roughness. Xerosis (dry skin) and Pruritus (itching) What is Xerosis? Dry skin (xerosis) is a condition that is found in all age groups but is most commonly experienced by elderly people. Young children and people using certain drug therapies, for example diuretics and androgen inhibitors, often suffer the disorder but in these cases it may be temporary. While the description ‘dry skin’ does not sound particularly serious, for those afflicted with the condition it can be quite distressing and certainly uncomfortable. In cases where the skin is exceptionally dry, xerotic eczema can develop with deep cracking of the skin and inflammation adding to the complication. Red, cracked and scaly skin is a symptom of xerosis and the unsightliness caused by this can be distressing for many sufferers. However, it is the itching which is the most aggravating symptom and this can lead to the skin surface being damaged, infection and inflammatory activity due to excessive scratching. Why does it happen? The condition is due to a lack of moisture in the skin and tends to be more prevalent in cold, dry winter conditions and air conditioned atmospheres. The areas of the body most commonly affected are the lower legs, back, arms and the waist and abdomen regions.
The greater prevalence of xerosis in elderly people is due to the age related, natural decline in sebaceous gland production of sebum not adequately maintaining the moisture and oil content of the skin. In males this decline does not really become effective until the age of about 80 but in females it begins after the menopause. Thus women as young as late 50’s or early 60’s are susceptible to the condition. Asteatotic eczema 1. What is asteatotic eczema? Asteatotic eczema is a type of eczema that is caused by dry skin that normally develops on the lower legs, lumbar area, buttocks or upper limbs in the elderly. Xerosis is dry skin resulting from lowered water and sebum secretion which becomes cutaneous pruritus with itchiness when it develops. Cutaneous pruritus becomes asteatotic eczema with a red rash or sores, as a result of irritation from scratching when it develops further. Early treatment is required for asteatotic eczema, because it progresses to nummular eczema. It is thought that asteatotic eczema occurs more frequently in the elderly because of an age related reduced ability for moisturizing that is due to the degeneration in intercellular lipids and a decline in sebum secretion. Recently, it has also appeared in young people as a result of excessive bathing and dryness caused by the use of heaters. 2. Cause The causes of asteatotic eczema are basically the same as those of xerosis and asteaosis. These disorders are attributed to dry skin, not having an adequate sebum coat due to the lowered skin functions and sebum secretion that occur with aging and some disorders. 3. Symptoms The symptoms of xerosis and asteatosis are dry, rough or cracked skin. In these cases, it is possible to control the symptoms by protecting the skin using a moisturizer. However, the symptoms of asteatotic eczema, which is an advanced stage of xerosis and asteatosis, are severe itchiness and red eczema caused by scratching. 4. Treatments
The treatment by asteatotic eczema is required on a long term basis because the symptoms are age related and difficult for a full recovery. Care of xerosis, asteatosis and asteatotic eczema Age-related asteatosis and xerosis are inevitable to some extent. However, for relieving symptoms even if only slightly, daily skincare and maintenance of the living environment are important. The considerations of asteatotic eczema in everyday life are basically the same as the considerations of asteatosis, due to the fact that asteatotic eczema often occurs with the deterioration of asteatosis. However, the drug treatments for asteatotic eczema and asteatosis are different. 1. When taking a bath or a shower When taking a bath or a shower, you have to get rid of extra corneum on the surface of the skin as well as dirt (dust, oil etc) while washing your body. In doing so, please note the following :
If the sebum is washed out by taking a shower or a bath, skin moisture increasingly evaporates and the skin dries more easily. This is due to the decline in the sebum lipogenesis ability in the case of asteatosis and asteatotics. So you need to use a moisturizer to moisten the skin. When there is still moisture in the skin after taking a shower or a bath, you should apply a moisturizer gently. There are a lot of commercial moisturizers available, you should select a moisturizer that best suits your skin type. Though the duration of moisture-retaining ability is different depending on the moisturizer, you need to apply these frequently to some extent. In addition, using moisturizing bath agents is also effective. 3. To reduce skin irritation
The dryness of the air often has the tendency to make your skin dry, especially when using a heater in a closed room because the humidity level will suddenly lower. It's better to make the air in the room moist, by letting in fresh air, using a humidifier, boiling a full kettle of water and putting a wet towel in the room (It is important to maintain the humidity level of the room to around 50-60%). 5. Sleep You should have plenty of sleep. When using an electric blanket or underblanket please note there is too much heat. Because it will increase itchiness by facilitating the flow of blood as well as progressing dry skin due to the evaporation of skin moisture. 6. Diets
You should keep your nails short and should not scratch affected areas, because scratching will definitely make symptoms worse. If you have severe itching with asteatotic eczema, cooling the affected area is an effective way in reducing the itchiness. 8. Exercise Try to build up a sweat with daily exercise, this will build up the strength of your sweat glands and make it easier for sweat to be released through your sweat glands. Sweat is a component on your skins’ sebum coat. It is also effective to refresh your body by taking a bedrock bath or a half body bath. 9. Stay sharp You need to continue skin care at least during the period when symptoms occur frequently (during winter). Even if the symptoms improve, the skin will return to the original dry condition immediately after stopping the skin care. During the summer if your skin doesn’t feel dry, you should occasionally continue the skincare to prevent the symptoms which will occur in the following autumn to winter that year. Before your symptoms become severe, you should protect your skin with the use of moisturizers such as Vaseline when you feel your skin drying, the reason being that symptoms become worse every year with the approach of winter. 10. Please talk to a skin specialist In the earlier phases of asteatosis, all you have to do is perform the measures mentioned above to maintain good skin condition to some extent. However, once you get skin inflammation, itchiness continues or skin conditions do not improve. In that case, you will need to be treated with moisturizer to make up for decreased lipid components and external medicine for itchiness and eczema. There are times when you will need to take internal medicine too, such as when you have severe itchiness. When you have severe symptoms or get eczema, please talk to a skin specialist. 11. Medication
The cause of asteatosis and asteatotic eczema is the decline in sebum lipogenesis ability. It has been proved that Maitake mushroom extract (lipid) enhances sebum lipogenesis of diminished sebaceous cells and stimulates sebum lipogenesis in sebaceous cells (in both the in vivo and in vitro experiments). Using this product is also effective in maintaining skin condition, which is not like existing cosmetics that protect the skin and preserve the skin moisture by applying moisturizer. The product that includes Maitake mushroom extract stimulates skin moisture itself and enhances the ability of self-defense by activating intrinsic sebum lipogenesis ability. |
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